What is Bimasone?
Bimasone is an injectable form of flumethasone, a chemical modification of prednisolone which possesses greater anti-inflammatory and gluconeogenic properties than the parent compound when compared on an equivalent basis. Due to the potency of Bimasone, dosage recommendations should be consulted prior to drug administration.
Indications
Bimasone is recommended for the various rheumatic, allergic, dermatologic, and other disease states which are known to be responsive to the anti-inflammatory corticoids.
Flumethasone has the highest relative glucocorticoid activity (120) and long duration of effect compared to other commonly used corticosteroids.
RELATIVE POTENCIES OF COMMONLY USED CORTICOSTEROIDS
| COMPOUND | RELATIVE GLUCOCORTICOID ACTIVITY | RELATIVE MINERALOCORTICOID ACTIVITY | DURATION OF EFFECTA (ALCOHOL FORM) |
|---|---|---|---|
| Flumethasone | 120 | 0 | L |
| Betamethasone | 25 | 0 | L |
| Dexamethasone | 25 | 0 | L |
| Isoflupredone | 25 | 25 | L |
| Triamcinolone acetonide | 30 | 0 | I |
| Triamcinolone | 5 | 0 | I |
| Fludrocortisone | 10 | 125 | I |
| Methylprednisolone | 5 | 0.5 | I |
| Prednisolone | 5 | 0.8 | I |
| Prednisone | 5 | 0.8 | I |
| Cortisol | 1 | 1 | S |
*Reprinted from Merck Veterinary Manual.
Benefits
- Bioequivalent to FluCort(R) (flumethasone)
- Consistent and Reliable - Non-compounded, Longer Shelf life
- Commercially Available
- Only FDA-approved Flumethasone ANADA # 200-612
Additional Safety Warnings
The close observation of animals under treatment with this drug is necessary.
Use of corticosteroids may result in inhibition of endogenous steroid production following drug withdrawal.
Corticosteroids administered to animals may induce the first stage of parturition when administered during the last trimester of pregnancy. Corticosteroids administered to dogs, rabbits and rodents during pregnancy have resulted in cleft palate in offspring. Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia and anasarca.
CONTRAINDICATIONS: Do not use in viral infections. Except for emergency therapy, do not use in animals with tuberculosis, chronic nephritis, cushingoid syndrome and peptic ulcers. Existence of congestive heart failure, diabetes and osteoporosis are relative contraindications.
Pack Size
| Item No. | Size |
|---|---|
| 1FLU021 | 100 mL |
*FluCort® is a registered trademark of Zoetis, Inc.