Dexamethasone Solution is a synthetic analogue of prednisolone, having similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects.
Each mL contains 2 mg dexamethasone, 500 mg polyethylene glycol 400, 9 mg benzyl alcohol, 1.8 mg methylparaben and 0.2 mg propylparaben as preservatives, 4.75% alcohol, HCI to adjust pH to approximately 4.9, water for injection q.s.
Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dexium® is indicated for the treatment of primary bovine ketosis and as an anti-inflammatory agent in the bovine and equine.
As supportive therapy, Dexium® may be used in the management of various rheumatic, allergic, dermatologic, and other diseases known to be responsive to anti- inflammatory corticosteroids. Dexium® may be used intravenously as supportive therapy when an immediate hormonal response is required.
- Potent: Approximately 20 times the anti-inflammatory activity of prednisolone and 70 to 80 times that of hydrocortisone
- Multi-species usage: Effective treatment for cattle and horses
- Fast absorption and powerful effect
- Choice of administration: IV or IM
- Safe: Approved by FDA
A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
- Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition.
- Except for emergency therapy, do not use in animals with chronic nephritis and hyper-corticalism (Cushing’s syndrome). Existence of congestive heart failure, diabetes, and osteoporosis are relative contraindications. Do not use in viral infections during the viremic stage.
- Overdosage of some glucocorticoids may result in sodium retention, fluid retention, potassium loss, and weight gain.
- Doses greater than those recommended in horses may produce transient drowsiness or lethargy in some horses.
- Use of corticosteroids, depending on the dose, duration, and specified steroid, may result in inhibition of endogenous steroid production following drug withdrawal.
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