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Dinoprost injection is the most-used prostaglandin in cattle.1

Category: Hormone/Reproduction

Species: Cattle

Active Ingredients: dinoprost

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What is ProstaMate®?

ProstaMate is a sterile solution that contains 5 mg/mL of dinoprost—a naturally occuring prostaglandin F2-alpha — and is indicated for use in cattle.

Dosage & Indications

ProstaMate Sterile Solution is indicated as a luteolytic agent. ProstaMate is effective only in those cattle having a corpus luteum, i.e., those which ovulated at least five days prior to treatment.

Class of CattleIndicationDosageRoute of Administration
Beef Cows, Beef Heifers & Replacement Dairy Heifers Estrus Synchronization 5 mL IM
Lactating Dairy Cows with a Corpus Luteum Unobserved (Silent) Estrus 5 mL IM
Cattle Treatment of Pyometra (chronic endometritis) 5 mL IM
Beef Cows, Beef Heifers & Replacement Dairy Heifers Abortion 5 mL IM
Lactating Dairy Cows Use with gonadorelin injection to synchronize estrous cycles to allow fixed-time artificial insemination (FTAI) 5 mL IM
Lactating Dairy Cows, Beef & Dairy Replacement Heifers, Suckled Beef Cows For use with EAZI-BREED CIDR® (progesterone intravaginal insert) Cattle Insert2 for synchronization of estrus 5 mL IM
* See label for complete product information

 Features & Benefits

  • A thoroughly researched molecule you can trust for safety & performance
  • No meat or milk withdrawal
  • A synchronized breeding program with ProstaMate can:
    • Improve pregnancy rates
    • Reduce time necessary for heat detection
  • The same formulation as Lutalyse® 3

Withdrawal Period

No milk discard or pre-slaughter drug withdrawal period is required for labeled uses in cattle.

Additional Safety Information

  • Not for use in humans.
  • Women of childbearing age, asthmatics, and persons with bronchial and other respiratory problems should exercise extreme caution when handling this product.
  • Accidental spillage on the skin should be washed off immediately with soap and water.
  • No vial stopper should be entered more than 20 times. For this reason, the 90 mL bottle should only be used for cattle. 
  • Nonsteroidal anti-inflammatory drugs may inhibit prostaglandin synthesis; therefore this class of drugs should not be administered concurrently.
  • Store at controlled room temperature 20° - 25°C (68° - 77°F). Protect from freezing.
  • Severe localized clostridial infections associated with injection of dinoprost tromethamine have been reported

Pack Size

List No.Pack SizeCase Size

1 Animalytix® 2017-2019 Ruminant Hormone SnapShot Report
2 EAZI CIDR® Cattle Insert are registered trademarks of Zoetis
3 Lutalyse® is a registered trademark of Zoetis